scorpions control

All scorpion species possess venom. In general, scorpion venom is described as neurotoxic in nature. One exception to this generalization is Hemiscorpius lepturus which possesses cytotoxic venom. The neurotoxins consist of a variety of small proteins that affect neuronal ion channels responsible for action potentials, which serve to interfere with neurotransmission in the victim. Scorpions use their venom to kill or paralyze their prey so that it can be eaten; in general it is fast-acting, allowing for effective prey capture. The effects of the sting can be severe.

The Emperor Scorpion's (Pandinus imperator) venom is not considered dangerous to humans

Scorpion venoms are optimized for action upon other arthropods, and therefore most scorpions are relatively harmless to humans; stings produce only local effects (such as pain, numbness or swelling). A few scorpion species, however, mostly in the family Buthidae, can be dangerous to humans. Among the most dangerous are Leiurus quinquestriatus, otherwise ominously known as the deathstalker, which has the most potent venom in the family, and members of the genera Parabuthus, Tityus, Centruroides, and especially Androctonus, which also have powerful venom. The scorpion which is responsible for the most human deaths is Androctonus australis, or the yellow fat-tailed scorpion, of North Africa. The toxicity of A. australis's venom is roughly half that of L. quinquestriatus, but despite a common misconception A. australis does not inject noticeably more venom into its prey. The higher death count is simply due to its being found more commonly, especially near humans. Human deaths normally occur in the young, elderly, or infirm; scorpions are generally unable to deliver enough venom to kill healthy adults. Some people, however, may be allergic to the venom of some species. Depending on the severity of the allergy, the scorpion's sting may cause anaphylaxis and death. A primary symptom of a scorpion sting is numbing at the injection site, sometimes lasting for several days. Scorpions are generally harmless and timid, and only voluntarily use their sting for killing prey, defending themselves or in territorial disputes with other scorpions. Generally, they will run from danger or remain still.

Scorpions are able to regulate how much venom is injected with each sting using striated muscles in the stinger, the usual amount being between 0.1 and 0.6 mg. There is also evidence to suggest that scorpions restrict the use of their venom using it only to subdue large prey, or prey that struggles. It has been found that scorpions have two types of venom: a translucent, weaker venom designed to stun only, and an opaque, more potent venom designed to kill heavier threats. This is likely because it is expensive in terms of energy for a scorpion to produce venom, and because it may take several days for a scorpion to replenish its venom supply once it has been exhausted.[11][12]

There is currently no scorpion equivalent of the Schmidt Sting Pain Index, because nobody has yet classified the levels of pain inflicted by different scorpion stings. This is probably because of the risk involved with some species, such as Androctonus australis or Leiurus quinquestriatus. However, envenomation by a mildly venomous species like Pandinus imperator or Heterometrus spinifer is similar to a bee sting in terms of the pain and swelling that results. A sting on the thumb from a relatively non-dangerous scorpion often feels like the victim has accidentally struck their thumb with a hammer whilst driving in a nail. A sting on the thumb from a truly dangerous scorpion can feel much worse, as though the victim had hammered a nail right through their thumb.[citation needed] It should be noted that the physical effects of a sting from a medically significant scorpion are not limited to the pain inflicted: there can be bradycardia, tachycardia or in severe cases pulmonary edema.

The stings of North American scorpions are rarely serious and usually result in pain, minimal swelling, tenderness, and warmth at the sting site. However, the Arizona bark scorpion Centruroides sculpturatus, which is found in Arizona and New Mexico and on the California side of the Colorado River, has a much more toxic sting. The sting is painful, sometimes causing numbness or tingling in the area around the sting. Serious symptoms are more common in children and include abnormal head, eye, and neck movements; increased saliva production; sweating; and restlessness. Some people develop severe involuntary twitching and jerking of muscles. Breathing difficulties may occur. These symptoms usually subside within 48 hours, although stings from bark scorpions can be life-threatening.[13]

The stings of most North American scorpions require no special treatment. Placing ice on the wound reduces pain, as does an ointment containing a combination of an antihistamine, an analgesic, and a corticosteroid. Centruroides stings that result in serious symptoms may require the use of sedatives, such as midazolam, given intravenously. Centruroides antivenin rapidly relieves symptoms, but it may cause a serious allergic reaction or serum sickness. The antivenin is available only in Arizona. In Trinidad the leaf juice of Eclipta prostrata is used for scorpion stings. Any effect of plants that are used against scorpion stings may be due to symptomatic relief – analgesic, anti-inflammatory, antipruritic effects, in addition to other biological activities. Some compounds from plants used for general inflammation also inhibit enzymes (like phospholipase A2) from snake and scorpion venom. Some of these plant compounds are hypolaetin-8-glucoside and related flavanoids.

Professor Moshe Gueron was the first to investigate the cardiovascular effects of a severe scorpion sting.[citation needed] Thousands of stung patients were reviewed. Thirty-four patients with severe scorpion stings were reviewed and pertinent data related to the cardiovascular system such as hypertension, peripheral vascular collapse, congestive heart failure or pulmonary edema were analyzed. The electrocardiograms of 28 patients were reviewed; 14 patients showed "early myocardial infarction-like" pattern. The urinary catecholamine metabolites were investigated in 12 patients with scorpion sting. Vanylmandelic acid was elevated in seven patients and the total free epinephrine and norepinephrine in eight. Six of these 12 patients displayed the electrocardiographic "myocardial infarction-like" pattern. Nine patients died and the pathological lesions of the myocardium were reviewed in seven. Also, Gueron reported five cases of severe myocardial damage and heart failure in Scorpion sting from Beer-Sheba, Israel. He described hypertension, pulmonary oedema with hypertension, hypotension, pulmonary oedema with hypotension and rhythm disturbances as five different syndromes that may dominate the clinical picture in scorpion sting victim. He suggested that all patients with cardiac symptoms should be admitted to an intensive cardiac unit. A few years later, in 1990, he reported poor contractility with low ejection fraction, decreased systolic left ventricular performance, lowered fractional percentage shortening observed in echocardiographic and radionuclide angiographic study. Gueron was questioned regarding the value of giving antivenin, and he replied that although it is freely available, all cases of scorpion sting are treated without it, and there had not been a single fatality in 1989.[14]

Accurate statistics on the incidence of scorpion envenomations worldwide are not available. Morbidity and mortality data have generally been based on victims entering hospitals and do not therefore account for the large number of unreported envenomations. Based on data from the 1940s, estimates for the number of worldwide deaths from scorpion stings ranged up to 5,000 per year. However, estimates from the late 1980s put the numbers of scorpion stings worldwide at around 100,000, with about 800 deaths per year.[15]